Cell-Based Transplantation versus Cell Homing Approaches for Pulp-Dentin Complex Regeneration

Cell-Based Transplantation versus Cell Homing Approaches for Pulp-Dentin Complex Regeneration

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Regenerative dentistry has paved the way for a new era for the replacement of damaged dental tissues.Whether the causative factor is dental caries, trauma, stuart products emcelle tocopherol or chemical insult, the loss of the pulp vitality constitutes one of the major health problems worldwide.Two regenerative therapies were introduced for a fully functional pulp-dentin complex regeneration, namely, cell-based (cell transplantation) and cell homing (through revascularization or homing by injection of stem cells in situ or intravenously) therapies, with each demonstrating advantages as well as drawbacks, especially in clinical application.The present review is aimed at elaborating on these two click here techniques in the treatment of irreversibly inflamed or necrotic pulp, which is aimed at regenerating a fully functional pulp-dentin complex.